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.406 Ventures secures $265M for fifth fund | TechCrunch

Feb 20, 2024 - techcrunch.com
Boston-based venture firm .406 Ventures has closed its fifth fund with $265 million in capital commitments. The firm, which invests in healthcare, data and AI, and cybersecurity startups, was founded by Liam Donohue, Maria Cirino, and Larry Begley. The new fund is backed by new and existing limited partners, including university endowments, foundations, pension plans, and strategic investors. Over its 18-year history, the firm has raised more than $1.4 billion across five core funds and three opportunity funds.

Donohue noted that the firm's focus remains the same, but they are seeing more repeat founders seeking new investments. The firm has a portfolio of 87 companies, many of which have exited or gone public. The new fund has already invested in four companies, including Portrait Analytics, and plans to invest in over 20 more. The firm considers various factors when investing, such as infrastructure plans and potential vulnerabilities in the industries they focus on.

Key takeaways:

  • .406 Ventures, a Boston-based venture firm, has closed its fifth fund with $265 million in capital commitments.
  • The firm, which focuses on investing in enterprise-focused startups in healthcare, data and AI, and cybersecurity, has raised more than $1.4 billion across its five core funds and three opportunity funds.
  • Unlike previous funds, the firm is seeing more repeat founders coming back for new investments, with a third of the fourth fund being repeat founders.
  • .406 Ventures has already made investments in four companies from the new fund, including Portrait Analytics, and plans to invest in more than 20 companies with the new fund.
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