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AI can help screen for cancer—but there’s a catch

Sep 15, 2023 - technologyreview.com
The article discusses the potential of AI in revolutionizing cancer detection and the risk of overdiagnosis. Microsoft has partnered with digital pathology company, Paige, to build the world's largest image-based AI model for identifying cancer. However, while AI-supported models have shown to reduce workload and detect more cancers, studies have shown no significant difference in mortality rates between those who underwent cancer screening and those who did not. The article suggests that the benefits of screening for some may be outweighed by the harms for others who don’t benefit, leading to overdiagnosis.

Adewole Adamson, a dermatologist and researcher, believes AI-assisted screening will lead to more overdiagnosis as the goal should be to find cancers that will ultimately kill people, not just find more cancer. However, AI could potentially help address the problem of overdiagnosis by using information embedded in medical records to examine the trajectories of different patients’ cancers over time. Adamson suggests adding a third category to the data that the algorithms learn from: “Maybe cancer”, which would encompass slides or images that provoke disagreement among experts.

Key takeaways:

  • Microsoft has partnered with a digital pathology company, Paige, to build the world’s largest image-based AI model for identifying cancer, using a training data set of 4 million images.
  • AI-supported cancer screening models have shown promising results, reducing workload by 44% and detecting 20% more cancers in a recent clinical trial.
  • However, there are concerns that AI-assisted screening could lead to overdiagnosis, as it may not be able to distinguish between lethal and nonlethal cases of cancer.
  • Adewole Adamson, a dermatologist and researcher, suggests that AI could potentially help address the problem of overdiagnosis by adding a third category to the data that the algorithms learn from: 'Maybe cancer'.
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