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From high school science project to $18.3M: AI-accelerated enzymes are coming for fast fashion’s plastic waste | TechCrunch

Mar 05, 2025 - techcrunch.com
Epoch Biodesign, a U.K. startup founded by Jacob Nathan, has secured $18.3 million in Series A funding to scale up production of plastic-eating enzymes. Originating from Nathan's high school project, the company aims to transfer its biorecycling process from the lab to its first production facility, capable of processing 150 tonnes of waste annually. The startup plans to double its team size within a year and expects commercial-scale production by 2028. Epoch uses generative AI to accelerate the discovery of enzymes that can break down plastics, focusing initially on polyester and two types of nylon. The AI-driven approach has enabled significant speed improvements in enzyme performance, reducing costs and enhancing recycling efficiency.

Epoch's biorecycling process is energy-efficient, requiring lower temperatures and yielding high recovery rates of reusable materials. The startup's method also avoids unwanted side products, further reducing costs. With a strategic investment from Inditex, Epoch aims to address the fashion industry's plastic waste problem by producing materials indistinguishable from current synthetic options. The Series A round, led by Extantia Capital, brings Epoch's total capital raised to $34 million. The company is focused on making synthetic plastic from recycled materials rather than fossil carbon, with plans to expand enzyme design to tackle other types of plastic waste in the future.

Key takeaways:

  • Epoch Biodesign, a U.K. startup, has secured $18.3 million in Series A funding to scale up production of plastic-eating enzymes.
  • The startup uses generative AI to accelerate the discovery of biological catalysts that can break down plastic waste, achieving significant speed improvements in enzyme performance.
  • Epoch's biorecycling process is energy-efficient, cost-effective, and yields high recycling rates, making it competitive with virgin plastic production.
  • The startup has partnered with Inditex to improve the sustainability of the fashion industry, focusing initially on recycling synthetic fabrics like polyester and nylon.
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