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GitHub - wangyi-fudan/wyGPT: Wang Yi's GPT solution

Dec 17, 2023 - github.com
The article discusses the results of a study on the EGFR gene mutation status in NSCLC patients. The study found that 52.2% of patients were positive for at least one EGFR mutation, and the majority were treated with EGFR-TKIs. The median progression-free survival (PFS) was 9.0 months and the median overall survival (OS) was 21.5 months. The EGFR mutation status was identified as an independent prognostic factor for PFS.

The article suggests that EGFR mutation sequencing is a cost-effective screening procedure for early-stage NSCLC. It proposes that EGFR gene mutations could be an independent risk factor for PFS and OS in advanced NSCLC patients, making it a potential target for treatment management. The study was conducted by JINSON Pharmaceuticals and the Department of Oncology at The University of Texas MD Anderson Cancer Center.

Key takeaways:

  • The wyGPT model is a result of 2.5 years of continuous work and is optimized for a single GPU.
  • The EGFR gene mutation status in NSCLC patients was analyzed and found to be a significant independent prognostic factor for progression-free survival.
  • The EGFR mutation sequencing from NSCLC patients is a cost-effective screening procedure for detecting EGFR mutations in the early stages of NSCLC.
  • EGFR gene mutations could be considered as an independent risk factor for progression-free survival and overall survival in patients with advanced NSCLC, making it a potential target for management.
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