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Meet 'Coscientist,' your AI lab partner

Dec 20, 2023 - new.nsf.gov
An AI-driven system named "Coscientist" developed by a team at Carnegie Mellon University has autonomously learned about Nobel Prize-winning chemical reactions and designed a successful laboratory procedure to execute them. The AI system was able to plan, design, and execute complex reactions, including palladium-catalyzed cross couplings, in a matter of minutes. The research, published in Nature, highlights the potential of AI in accelerating scientific discoveries and improving the reliability of experimental results.

Coscientist uses large language models to extract meaning and patterns from massive amounts of data, and it can control robotic lab equipment to carry out experiments. The system demonstrated "chemical reasoning," using publicly available chemical information to guide its actions. It successfully synthesized commonly used substances such as aspirin, acetaminophen, and ibuprofen. The researchers believe that AI-assisted systems like Coscientist can democratize resources and understanding in the scientific field, significantly lowering the entry barrier for various fields.

Key takeaways:

  • An artificial intelligence system named Coscientist, developed by a team at Carnegie Mellon University, was able to autonomously learn about Nobel Prize-winning chemical reactions and design a successful laboratory procedure to make them.
  • Coscientist was able to perform complex reactions known as palladium-catalyzed cross couplings, which play a significant role in the pharmaceutical development process and other industries that use carbon-based molecules.
  • The AI system demonstrated the ability to accurately plan chemical procedures, write computer code to carry out experiments, analyze resulting data, and even correct its own mistakes.
  • The researchers believe that AI-assisted systems like Coscientist can accelerate scientific discovery, improve the replicability and reliability of experimental results, and democratize access to scientific resources and understanding.
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