Sign up to save tools and stay up to date with the latest in AI
bg
bg
1

Preventing the weaponization of AI-designed proteins

Mar 11, 2024 - statnews.com
The failure of Amylyx Pharmaceuticals’ drug Relyvrio in clinical trials is likely to lead to its withdrawal from the market, raising questions about the FDA's approval process and the future of Amylyx. Meanwhile, Alumis' drug ESK-001 showed promising results in a Phase 2 trial for psoriasis, with plans to launch Phase 3 studies soon. Researchers are calling for ethical handling of AI-mediated protein engineering to prevent potential use as bioweapons, with over 100 scientists signing a manifesto committing to responsible research.

A new online marketplace, aRukon, is set to launch this year to help researchers sell unused animal samples, aiming to reduce waste and prevent unnecessary animal deaths. Lundbeck’s experimental drug showed promise in slowing the progression of multiple system atrophy, despite missing the primary endpoint in a study. Other news includes BeiGene filing patent suits against Sandoz and MSN Group, and Novartis’ BTK inhibitor showing positive results in a dermatology trial.

Key takeaways:

  • Amylyx Pharmaceuticals’ drug Relyvrio failed to show any benefit over a placebo in large clinical trials, leading to potential withdrawal from the market and raising questions about FDA's policy of “regulatory flexibility”.
  • Alumis' lead drug candidate ESK-001 showed promising results in a Phase 2 trial for psoriasis, with plans to launch Phase 3 studies in the coming months.
  • Over 100 scientists have signed a manifesto called “Responsible AI x Biodesign”, calling for safe and ethical handling of AI-mediated protein engineering to prevent potential use as bioweapons.
  • A new online marketplace, aRukon, is launching globally to help researchers sell unused animal samples to other labs, aiming to reduce waste, save money, and prevent unnecessary animal deaths.
View Full Article

Comments (0)

Be the first to comment!