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Rakovina Therapeutics and Variational AI Strengthen Partnership

Feb 26, 2025 - financialpost.com
Rakovina Therapeutics Inc. has reaffirmed its strategic partnership with Variational AI following the latter's successful $5.5 million financing round led by Nimbus Synergies, with contributions from Merck Global Health Innovation Fund and others. This collaboration aims to leverage AI-powered generative models to accelerate the discovery of novel kinase inhibitors targeting DNA-damage response pathways, crucial for cancer treatment. The partnership has already identified a shortlist of ATR inhibitors, which could selectively destroy cancer cells while sparing healthy ones, with preclinical results expected in Q2 2025.

Variational AI's Enki™ platform, a foundation model for small-molecule drug discovery, is central to this collaboration, enhancing Rakovina's AI-driven approach to developing next-generation cancer therapies. The partnership exemplifies the transformative potential of AI in drug discovery, with plans to expand AI-driven discovery efforts and advance promising candidates toward preclinical development. Rakovina aims to harness AI to bring more effective cancer treatments to patients, marking a pivotal step in the fight against cancer.

Key takeaways:

  • Rakovina Therapeutics and Variational AI have strengthened their partnership to accelerate AI-powered cancer drug development.
  • Variational AI raised $5.5 million in an oversubscribed financing round led by Nimbus Synergies, with participation from Merck Global Health Innovation Fund and others.
  • The partnership focuses on using AI to discover novel kinase inhibitors targeting DNA-damage response pathways, with preclinical results expected in Q2 2025.
  • Variational AI's Enki™ platform is central to this collaboration, enhancing small-molecule drug discovery through AI-driven generative models.
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