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This Chinese MIT Physicist Uses AI To Find New Drugs. Next Up: Solar Panels And EV Batteries

Jan 28, 2025 - forbes.com
Wen Shuhao, cofounder and chairman of Xtalpi, played a key role in accelerating the development of Pfizer's Covid oral drug, Paxlovid, using AI and quantum physics-based calculations. His company, Xtalpi, initially focused on AI-driven drug discovery, achieving significant success and forming partnerships with major pharmaceutical companies. Now, Wen aims to apply Xtalpi's technology to other industries, specifically solar panels and electric vehicle batteries, expecting these new ventures to match the revenue of their drug discovery business within three years. Xtalpi's approach combines quantum physics algorithms, AI, and robotics to enhance efficiency and accuracy in discovering new materials and drugs.

Despite some skepticism about the reliability of quantum mechanical simulations in drug discovery, Xtalpi has attracted substantial investment and partnerships, including a strategic collaboration with Microsoft China. The company went public in Hong Kong in 2024 and continues to invest heavily in research and development. Wen believes that AI will become a fundamental tool in both the pharmaceutical and materials industries, and he is confident in Xtalpi's ability to excel in both areas. The company is also exploring the commercialization of advanced materials like perovskite for solar panels and solid-state batteries for electric vehicles, leveraging its technology to overcome production challenges.

Key takeaways:

  • Wen Shuhao, cofounder of Xtalpi, helped speed up the development of Pfizer's Covid oral drug, Paxlovid, using AI and quantum physics algorithms.
  • Xtalpi is expanding its technology to disrupt the solar panel and electric vehicle battery industries, aiming for revenue parity with its drug discovery business within three years.
  • Xtalpi's AI and quantum physics algorithms are designed for early-stage drug discovery, speeding up the process by about 50%, but human trials remain the most challenging part of drug development.
  • Xtalpi is also exploring new materials discovery, including energy-efficient solar panels and next-generation EV batteries, with significant commercial potential.
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